The first-of-its-kind gene therapy dramatically reduced the levels of misfolded proteins in some clinical trial participants for up to six months and lowered levels in all participants for up to one year. Researchers have successfully deactivated the gene in human patients by treating them with CRISPR gene-editing technology, clearing …
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New CRISPR technique causes several unintended mutations in fruit flies
The study found that CRISPR-Nickase, which changes only one allele of a given gene, improves the efficiency of gene editing compared to CRISPR-Cas9. CRISPR-Cas9 has revolutionized biology and healthcare. It hijacks the bacterial immune defense system to precisely edit the genome. But the method is not perfect. It can insert …
Read More »Clinical trials take a bite out of the CAR T Therapy market
All things considered, about a quarter of treatment-eligible lymphoma patients make exploratory (and free) decisions. Despite the new underwriting of two disease drugs that use CAR T cells to treat lymphoma, only 25% of eligible patients actually choose to enter clinical trials instead of going through open-label treatment. This follows …
Read More »Startups Get Ready for the Rush for Health Data
Associations are set to consider blockchain development to allow individuals to control and directly benefit from their genomic and clinical information. Shawna Williams: Whether you’ve never heard of IQVIA or not, the association probably knows a few things about you if you’re lucky enough to be in an anonymized structure. …
Read More »Synthetic RNA can make peptides, suggesting the beginnings of life
Researchers have engineered strands of RNA that can link amino acids together, suggesting a way in which RNA and proteins may have emerged together to form the earliest forms of life. RNA has long been considered a key molecule in the primordial soup that was Earth a few billion years …
Read More »DNA damage seen with unprecedented clarity
The new tool, called PRISM, draws on virus-host interactions and the DNA repair pathway to help researchers visualize how cellular stress can contribute to neurodegenerative disease. Unlike most cells, mature neurons do not divide. Because mutations often arise through error-prone mechanisms of cell division, scientists once believed that these neurons …
Read More »Medical labs file lawsuit against US government over health care fees
Scheduled test installments are unreasonably cheap and can drive small businesses out of business, according to the American Clinical Laboratory Association. U.S. Naval Forces, Wikimedia Mass Communication Specialist 2nd Class Chelsea A. Blom took the picture. The bureaucratic health insurance program for seniors known as Medicare has been sued by …
Read More »US ramps up supply of monkeypox drugs as Nordic country of Bavaria boosts supply capacity via Grand River
The Department of Health and Human Services said earlier this week that it would make the final 442,000 injections of the initial supply of monkeypox vaccine available earlier than expected. (Photo by Mario Tama/Getty Images) In a flash monkeypox report on Thursday, the United States said it would provide an …
Read More »Breaking: CDC’s Public Health and Prevention Fund May Be Eliminated
House of Representatives on Wednesday, would repeal the Obamacare-funded initiative if it becomes law. The Centers for Disease Control and Prevention (CDC) could face funding cuts of up to 12 percent if the Medicare Act passed by the US House of Representatives today (May 4) becomes law. The Affordable Care …
Read More »Within two months, only five patients received Gilead’s CAR T-cell Therapy
More than 200 individuals are on waiting lists for the $373,000 treatment as the clinic struggles to resolve issues with the insurance agency. According to a report distributed last Thursday (Dec. 14) in Bloomberg, Gilead Sciences’ blood disease treatment was given to only five patients within two months of its …
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